Causes, Risk Factor and Symptoms of Obstetrics in Septic Shock

Septic shock can occur due to gram-positive bacterial infections, viruses, or fungi. Most of septic shock due to gram-positive gram-negative bacteria: Escherichia coli, pseudomonas aeroginos, bacterioid, Klebsiella species, and Serratia. Escherichia coli, pseudomonas aeroginos, bacterioid who issued endotoxin is fosfo-lipo-polysaccharides are separated from the walls of cells undergoing lysis. The same picture also occur due to an exotoxin of beta-hemolytic streptococci, anareob, and clostridia.

The microorganisms secrete endotoxin can activate the complement system and cytokines, initiate an inflammatory reaction. Sepsis causes vasodilation, vascular peripheral resistance decreased, and hypotension. Furthermore, the distribution of blood flow less / ugly so that blood perfusion to organs inadequate cause multiple organ tissue damage and death. Inflammatory mediators increase the permeability of capillaries so that fluid out of the blood vessels, specifically the pulmonary parenchyma will cause pulmonary edema.

During sepsis pneumocytes surfactant production will be disrupted which causes alveoli collapse and lead to severe hypoxemia called acute respiratory distress syndrome (ARDS).

Endotoxin off due to increased permeability of lysosomes and cytotoxic. Furthermore, in a few minutes can occur stimulation of the adrenal medulla and sympathetic nerve as well as constriction of arterioles and venul. Furthermore, local acidosis which can cause dilated arterioles, but constricting venul and if it continues resulting in the damming of blood capillaries, bleeding due to the damming of the gastric, liver, kidneys and lungs.


Causes of Obstetrics in Septic Shock

• Septic abortion
• Premature rupture of membranes / chorioamnionitis
• Postpartum infection: manipulation and instrumentation
• Trauma
• Retained placenta
• Puerperal sepsis
• Acute pyelonephritis

Risk Factor

• Premature rupture of membranes
• The rest of the conceptions were not out
• Instrumentation urogenital tract

Symptoms of Septic Shock

• Shiver
• Hypotension
• Mental disorders
• Tachycardia
• Tachypnea
• Red leather
• Cold and wet skin, bradycardia, and cyanosis (when the shock gain weight)

Clinical Symptoms

Septic shock occurs in two main phases, namely:

1. Reversible Phase

• Fever Phase. Symptoms: hypotension, tachycardia, pyrexia and chills, skin looks red and hot. The patient is still conscious and leukocytosis occur within a few hours.
• Cold phase: Symptoms: cold skin, wrinkled, cyanosis, purpura, jaundice, progressive loss of consciousness, and coma.

2. Irreversible Phase
Prolonged hypoxia cells that cause the symptoms of metabolic acidosis, acute renal failure, heart failure, pulmonary edema, adrenal failure, and death.

Causes, Risk Factor of Obstetrics in Septic Shock